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The antidiabetic drug metformin activates the amp-activated protein kinase cascade via an adenine nucleotide-independent mechanism.

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the authors report experiments that support the hypothesis that postulates that metformin s biological effect in cancer biology is through inhibition of the mitochondrial complex i nadh dehydrogenase.

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for patients without health insurance, diabetes medication costs 8 to 200 per month or more for metformin taken along with another diabetes drug, such as one of a class of medications called sulfonylureas -- such as brand name glucotrol or diabinese -- or one of a class of drugs called alpha-glucosidase inhibitors, such as brand names precose and glyset.


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